salvatore monaco univr

Salvatore Monaco, 28, from Italy AC Perugia Calcio, since 2015 Centre-Back Market value: €350Th. Salvatore Monaco MD, PhD. The diagnosis of peripheral neuropathies can be challenging with consequent difficulties in patients’ management. Salvatore has 3 jobs listed on their profile. Importance: University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. We aimed at investigating... An asymptomatic 74-year-old woman, on follow-up for a carotid body tumour, showed MRI focal restricted diffusion confined to the left temporal and occipital cortices. We describe the case of a relapsing-remitting MS patient whose history was characterized by failure of several the... Background: Dimethyl fumarate (DMF) is a disease-modifying drug for relapsing-remitting multiple sclerosis. QTc interval in patients with multiple sclerosis: An inference from the insula of Reil? Comedian. The first outbreak occurred in the northeastern region of Italy surrounding the Po River and was caused by the Po River lineage 1 st... Background: PoTS: Long term follow-up of an Italian cohort, 47. Int. Università degli Studi di Verona Via dell'Artigliere, 8 37129, Verona Partita IVA 01541040232 | Codice Fiscale 93009870234 Pain is an important non-motor symptom in several neurological diseases, such as Parkinson's disease, cervical dystonia, amyotrophic lateral sclerosis, severe acquired brain injury, disorders of consciousness and dementia, as well as in oncology and neuroinfectivology. © 2008-2020 ResearchGate GmbH. However, the mortality of central nervous system (CNS) complications and opportunistic infections is still high in untreated HIV-infected individuals or in pat... Charcot–Marie–Tooth disease (CMT) is an heterogeneous group of hereditary neuropathies characterized by weakness and atrophy of the limbs, loss of sensation and absent or reduced tendon reflexes. Some authors suggested a multifactorial genesis of imbalance in patient affected by Charcot–Marie–Tooth disease (CMT) caused not only by reduced proprioceptive input but also by a vestibular impariment. Sci. Human endogenous retroviruses‐K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disorder, is characterized by remarkable phenotypic Salvatore Monaco. A good friend can help you in need, 49. The aim of the present study is to assess a possible association of the electrocardiografic (ECG) markers of the dispersion of repolarization with the type of stroke, involvement of insula, neuro... We would like to thank John Madias for his interest in our review about the mystery of the pathogenesis of Takotsubo cardiomyopathy (TC) .¹ We agree with his semantic restraint of the eponym Wellens electrocardiographic (ECG) pattern, which needs a contextual disambiguation. 2020, 21, 880 2 of 10 of the normal cellular prion protein (PrP) into an abnormal misfolded pathological form, termed disease-associated PrP. The aims of this study were to evaluate in consecutive patients with acute stroke and atrial fibrillation (1) the incidence of early HT, (2) the time to initiation of ant... Cerebrospinal fluid (CSF) biomarkers are currently included in the diagnostic criteria for Alzheimer's disease (AD), in particular, decreased concentrations of amyloid-β peptide 1- 42 (Aβ42) in the CSF, coupled with increased levels of tau and phosphorylated tau proteins, are supportive of AD diagnosis. Laser-evoked potentials (LEPs) are useful neurophysiological tools for investigating the A-delta sensory peripheral fibers and the central nociceptive pathway. Due to our privacy policy, only current members can send messages to people on ResearchGate. All rights reserved. Methods The aim of this study was to explore the current diagnostic role of sural nerve biopsy and to compare pathological findings with serum neurofilament light chain levels (NfL) as biomarkers of axonal damage. Tesi specialistica/ciclo unico thesis, Università degli Studi di Verona. The purpose of this study was to evaluate serum and cerebrospinal fluid cytokine/chemokine p... Cryoglobulins are circulating immunoglobulins that reversibly precipitate at temperatures below 37 °C. The degree of paresis was compared between t... Background: The QTc interval is the electrocardiographic manifestation of ventricular depolarization and repolarization. Visual electrophysiology. The Takotsubo cardiomyopathy is often considered autochthonous to the heart, although the primary problem may be not in the heart muscle itself. The cause of the cerebrogenic QT prolongation Since 1800s there are reports of post-traumatic anosmia, but few studies investigated post-traumatic gustatory deficit and adopted validated evaluation tests. 3 likes. Monaco S(1), Ferrari S, Gajofatto A, Zanusso G, Mariotto S. ... Verona 37134, Italy. MRI, laboratory and clinical investigations were highly suggestive of an active inflammatory demyelinating disease. Author information: (1)Section of Clinical Neurology, Department of Neurological and Visual Sciences, University of Verona, Verona, Italy. To investigate the relationship among cortical radiologic changes, the number of early relapses (ERs), and the long-term course of multiple sclerosis (MS). and Zanusso, Gianluigi (correl.) We reviewed clinical and neurophysiological characteristics and outcome after a long term follow-up of our cohort. Major concerns regard the risk of developing progressive multifocal leukoencephalopathy (PML), and the occurrence of rebounds or disease activity after its discontinuation. “The study, conducted entirely in university health facilities in Verona with the fundamental role of the research team comprised of Sara Mariotto, Sara Carta, Silvia Bozzetti, Cecilia Zivelonghi, Daniela Alberti and Salvatore Monaco, is of paramount importance to our understanding of Covid-19, which has had such an impact on our daily lives. Normal values of electrophysiological study of vision, 40. Objective is to define a protocol and describe normative data. Disease-associated PrP can acquire different conformations, which, in combination with the The objective of this paper is to investigate whether... Background Objective: The increase of sinus heart rate of 30beats/min or greater occurring within 10min of head-up tilt test or standing, or a heart rate while upright of >120beats/min. Correspondence should be addressed to Salvatore Monaco, [email protected] Received 23 April 2012; Accepted 26 June 2012 Academic Editor: Domenico Sansonno We describe a patient with anti-IgLON5 syndrome, who presented with dysautonomia and sleep disorder, followed by subacute dementia. - Ruolo diagnostico delle proteine 14-3-3 e tau liquorali nelle malattie neurodegenerative. While the etiology of sCJD remains unknown, it has been hypothesi... Benign multiple sclerosis (BMS) definitions rely on physical disability level but do not account sufficiently for cognitive impairment which, however, is not rare. These changes are strictly associated with compartmentalized sustained inflammation within the brain parenchyma, the leptomeninges, and the cerebrospinal fluid. The introduction of highly active anti-retroviral therapy (HAART) led to a radical change in the natural history of HIV infection and of the associated neurological opportunistic infections. Although cognitive dysfunction is a relevant aspect of multiple sclerosis (MS) from the earliest disease phase, cognitive onset is unusual thus jeopardizing early and accurate diagnosis. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. * Aug 15, 1992 in Napoli, Italy To investigate the role of temporal lobe damage in MS patients suffering from epilepsy, by the application of advanced multimodal 3T magnetic resonance imaging... Infectious diseases frequently affect the peripheral nervous system by direct infiltration or indirect inflammatory response induced by the microorganisms. Main activities and responsibilities. The aim of this study was to investigate the correlation between the duration of the QTc interval and the brain lesion load at the level of the structures involved in superior autonomic control (insula, cingulate cortex and amygdala-hippocampus) in multiple sclerosis (MS) patients. Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples, Time for a consensus conference on pain in neurorehabilitation, Polio patients in Northern Italy, a 50 year follow-up, Assessing and treating pain in movement disorders, amyotrophic lateral sclerosis, severe acquired brain injury, disorders of consciousness, dementia, oncology and neuroinfectivology. The cerebellum is involved in motor execution. Since 40 years, study investigating a possible Autonomic Nervous System (ANS) involvement are reported. Athlete. The afferent visual pathway can be evaluated by the neurophysiologist using full-field ERG, transient or stationary P-ERG and pattern VEP. Chronic infection with hepatitis C virus (HCV) is associated with a large spectrum of extrahepatic manifestations (EHMs), mostly immunologic/rheumatologic in nature owing to B-cell proliferation and clonal expansion. (2003) [BM Tesi HA 0327]. He achieved the PhD degree in "Social Sciences and Statistics" at the Department of Social Sciences, University of Naples Federico II. The current investigation aims to obtain normative values of LEPs via pudendal nerve stimulation in healthy adult volunteers. Paroxysmal dysarthria-ataxia in remitting-relapsing Bickerstaff's-like encephalitis, Cellular and molecular mechanims involved in multiple sclerosis development ad progression. Clinical and imaging follow-up coupled with cerebrospinal fluid (CSF) and possibly serum profiling could provide information on disease activity and disability evolution in multiple sclerosis patients.  |  Among others, DMF impedes immune activation by shifting the balance between inflammatory and regulatory cell types and by inducing apoptosis-triggered lymphopenia. [email protected] Acquired demyelinating and inflammatory neuropathies encompass a number of acute and chronic autoimmune conditions characterized by variable degrees of clinical involvement. Case presentation: We here compare the clinical and laboratory findings observed in a cohort of MOG-Ab seropositive and seronegative cases and describe IgG subclass analysis results.... Background This early diagnosis is becoming possible using the real-time quaking-induced conversion (RT-QuIC) seeding assay, which detects minut... Background: Poliomyelitis was before the immunization an important medical problem. Aims: E-mail address: [email protected] Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy Azienda Ospedaliera Universitaria Integrata, Verona, Italy Salvatore Monaco (born 15 August 1992) is an Italian football player. Salvatore Monaco's 3 research works with 88 citations and 283 reads, including: Inflammatory intrathecal profiles and cortical damage in multiple sclerosis To date, the quantification of Aβ42 levels wi... IntroductionThe mechanism of action of fingolimod within the central nervous system and its efficacy in reducing/preventing both focal and diffuse grey matter (GM) damage in active multiple sclerosis (MS) are not completely understood. Peripheral nerve ultrasonography: Clinical use, 58. This Patients underwent clinical as... Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative motoneuron disease. Markers of dispersion of myocardial repolarization have been proposed to identify the patients at higher risk of malignant arrhythmic events. Methods: Vestibular-coclear nerve involvement in Charcot–Marie–Tooth disease: A pilot-study, Spinal arachnoid cyst as a cause of isolated, progressive, bilateral C5-C6 radiculopathy, Clinical efficacy, safety, and tolerability of fingolimod for the treatment of relapsing-remitting multiple sclerosis, Hepatitis C virus-associated neurocognitive and neuropsychiatric disorders: Advances in 2015, Brentuximab vedotin: Axonal microtubule's Apollyon, Regional Distribution and Evolution of Gray Matter Damage in Different Populations of Multiple Sclerosis Patients, Sporadic Creutzfeldt-Jakob Disease: Prion Pathology in Medulla Oblongata—Possible Routes of Infection and Host Susceptibility, Benign multiple sclerosis: Physical and cognitive impairment follow distinct evolutions, Neurological complications of HIV infection in pre-HAART and HAART era: a retrospective study, Acute inflammatory demyelinating polyneuropathy as a manifestation of chronic lymphoproliferative disorder of NK cells, 65. Director of the School of Neurology, University of Verona. Soldani, Daria and Monaco, Salvatore (rel.) A case of bilateral chronic optic neuropathy related to inverted papilloma of paranasal sinuses, 10. Aim of our pilot case-control study is to determine the prev... Fingolimod is a selective immunosuppressive agent approved worldwide for the treatment of relapsing-remitting multiple sclerosis (MS), a chronic and potentially disabling neurological condition. Disease-associated PrP can acquire di erent conformations, which, in combination with the Int. We retrospectively collected clinical and paraclinical data of 92 patien... Isolated REM sleep behaviour disorder is an early-stage alpha-synucleinopathy in most, if not all, affected subjects. After one month, the patient developed gait instability and cognitive d... Background: We report a case of a 65 year-old man which was admitted to the Multiple Sclerosis Center because of chronic bilateral blindness where the visual electrophysiology gave important clues for an unexpected diagnosi... Scotopic and photopic full field-Electroretinogram (ERG), pattern electroretinogram (PERG) and visual evoked potential (VEP) are stimulating and recording methods to evaluate the functionality of the different layers of retina and of the visual pathway from retina to visual cortex of the brain. Peripheral neuropathies (PN) are commonly observed in the course of HIV infection and represent the major neurological complication of the disease. To analyze the medical situation 50 years after acute polio. The olfactory neuroepithelium is located in the upper vault of the nasal cavity, lying on the olfactory cleft and projecting into the dorsal portion of the superior and middle turbinates beyond the mid-portion of the nasal septum. Verona University Italian. paratuberculosis (MAP) homologous to EBV and human epitopes (MBP85-98, IRF5424-434) in multiple sclerosis... Anti-myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) recently emerged as a potential biomarker in patients with inflammatory demyelinating diseases of the central nervous system. Human cases of WNV-associated fever and/or neurological disorders have been reported in Italy since 2008. Aims: Sleep disorders, bulbar dysfunction, and gait abnormalities are common presenting symptoms, and conventional brain MRI scanning is often u... Minifascicular neuropathy (MN) is a rare, autosomal recessive disease with prominent structural changes of peripheral nerves. It is composed of a variety of cell types including olfactory sensory neurons, supporting glial-like cells, microvillar... Purpose: Instead, similar to several Takotsubo‐like cardiac pathologies seen in acute neurological diseases, it may reflect the capacity of the nervous system to injure the heart. Documents Curriculum CV Monaco Italiano (pdf, it, 184 KB, 31/08/18) CV Salvatore Monaco Eng (docx, en, 37 KB, 28/08/18) Research interests; Topic Description Research area; Neurosciences Molecular mechanisms and biomarkers in neurodegenerative and neuroinflammatory disorders. P. I.V.A. [email protected]. Department of Neurological, Neuropsychological, Morphological and Movement Sciences, Hypothalamic-Bulbar MRI Hyperintensity in Anti-IgLON5 Disease with Serum-Restricted Antibodies: A Case Report and Systematic Review of Literature, Convergent pathological and ultrasound features in hereditary syndromic and non‐syndromic minifascicular neuropathy related to DHH, Intrathecal Inflammation in Progressive Multiple Sclerosis, Alpha-synuclein seeds in olfactory mucosa of patients with isolated rapid-eye-movement sleep behaviour disorder Running title: Olfactory mucosa α-syn RT-QuIC in iRBD, Statin-associated necrotizing autoimmune myopathy with concurrent myasthenia gravis, Sural nerve biopsy: current role and comparison with serum neurofilament light chain levels, Superior diagnostic performance of reduced-FOV DWI versus conventional DWI MRI in anti-NMDAR encephalitis, Epileptic seizures of suspected autoimmune origin: a multicentre retrospective study, Alpha-synuclein seeds in olfactory mucosa of patients with isolated rapid-eye-movement sleep behaviour disorder, Longitudinal serum neurofilament light chain (sNfL) concentration relates to cognitive function in multiple sclerosis patients, Nervous system: subclinical target of SARS-CoV-2 infection, Transmission of CJD from nasal brushings but not spinal fluid or RT-QuIC product: Low prion titers in human sCJD nasal brushings, Neuroimaging Findings in Chronic Hepatitis C Virus Infection: Correlation with Neurocognitive and Neuropsychiatric Manifestations, Neurodegeneration-Associated Proteins in Human Olfactory Neurons Collected by Nasal Brushing, Laser-Evoked Potentials to Pudendal Stimulation in Healthy Subjects: A Pilot Study, Important distinction between acute coronary syndromes and Takotsubo syndrome, Myelin uncompaction and axo‐glial detachment in chronic ataxic neuropathy with monospecific IgM antibody to ganglioside GD1b, Iron homeostasis, complement, and coagulation cascade as CSF signature of cortical lesions in early multiple sclerosis, Antibody response against HERV-W in patients with MOG-IgG associated disorders, multiple sclerosis and NMOSD, QTc Prolongation in Patients with Dementia and Mild Cognitive Impairment: Neuropsychological and Brain Imaging Correlations, Relevance of antibodies to myelin oligodendrocyte glycoprotein in CSF of seronegative cases, α‐Synuclein RT‐QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies, Increase of CSF inflammatory profile in a case of highly active multiple sclerosis, Increased NK Cell Count in Multiple Sclerosis Patients Treated With Dimethyl Fumarate: A 2-Year Longitudinal StudyImage_1.JPEGImage_2.JPEGImage_3.jpgTable_1.DOCX, Serum and CSF neurofilament light chain levels in antibody-mediated encephalitis, Clinical and neurophysiological serial assessments of brentuximab vedotin-associated peripheral neuropathy, Distinct serum and cerebrospinal fluid cytokine and chemokine profiles in autoantibody-associated demyelinating diseases, Lymphomatosis cerebri and anti-NMDAR antibodies: A unique constellation, Clinical practice: hepatitis C virus infection, cryoglobulinemia and cryoglobulinemic vasculitis, Effect of glatiramer acetate on cerebral grey matter pathology in patients with relapsing-remitting multiple sclerosis, Hemorrhagic Transformation in Patients With Acute Ischemic Stroke and Atrial Fibrillation: Time to Initiation of Oral Anticoagulant Therapy and Outcomes, Reappraisal of Aβ40 and Aβ42 Peptides Measurements in Cerebrospinal Fluid of Patients with Alzheimer’s Disease, The effect of fingolimod on focal and diffuse grey matter damage in active MS patients, Response to Association of Prolonged QTc Interval With Takotsubo Cardiomyopathy: A Neurocardiac Syndrome Inside the Mystery of the Insula of Reil, Serum and CSF neurofilament light chain levels in patients with acquired peripheral neuropathies, The cortical damage, early relapses, and onset of the progressive phase in multiple sclerosis, The dispersion of myocardial repolarization in ischemic stroke and intracranial hemorrhage, Author Response to LTE CLC 22970 of John Madias: Brain‐heart pathway to injury in takotsubo syndrome, Association of prolonged QTc interval with Takotsubo cardiomyopathy: A neurocardiac syndrome inside the mystery of the insula of Reil, Post-traumatic taste disorders: a case series, Humoral immunity response to HERV‐K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases, Mycobacterium avium subspecies paratuberculosis and myelin basic protein specific epitopes are highly recognized by sera from patients with Neuromyelitis optica spectrum disorder, Brentuximab vedotin-induced peripheral neuropathy: looking at microtubules, Clinical Neuropathology image 1-2018: Golgi silver staining, the black reaction, Clinical spectrum and IgG subclass analysis of anti-myelin oligodendrocyte glycoprotein antibody-associated syndromes: a multicenter study, Antibody response against HERV-W env surface peptides differentiates multiple sclerosis and neuromyelitis optica spectrum disorder, MOG antibody seropositivity in a patient with encephalitis: Beyond the classical syndrome, Dimethyl fumarate: A possible exit strategy from natalizumab treatment in patients with multiple sclerosis at risk for severe adverse events, NEURODEGENERATION-ASSOCIATED PROTEINS IN HUMAN OLFACTORY NEURONS, A case of acute fulminant multiple sclerosis treated with alemtuzumab, Microglial and Neuronal TDP-43 Pathology in Anti-IgLON5-Related Tauopathy, HCV RNA Genomic sequences and HCV‐E2 glycoprotein in sural nerve biopsies from HCV‐infected patients with peripheral neuropathy, Heterogeneity of Cortical Lesion Susceptibility Mapping in Multiple Sclerosis, Prion Strain Characterization of a Novel Subtype of Creutzfeldt-Jakob Disease, Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: A combined CSF and MRI study. Blood Cancer Journal is a peer-reviewed, open access online journal publishing pre-clinical and clinical work in the field of hematology with ramifications into translational biology research down to new therapies. feed.stats.entry-description ????? Objective: Unlikely Somatosensory Evoked Potentials and conventional electroneurography, Nd-Yap laser stimulator LEP selectively stimulate small myelinated (Aδ) and unmyelinated (C) fibers. Type-II cryoglobulins consist of monoclonal IgM/polyclonal IgG immune complexes (ICs), whereas in type-III cryoglobulins both IgM and IgG are polyclonal. discrimina... Electroretinogram (ERG), pattern electroretinogram (PERG) and visual evoked potential (VEP) are stimulation and recording methods to evaluate the functionality of the different elements of retina and visual pathways. Since its identification in 1989, hepatitis C virus (HCV) has emerged as a worldwide health problem with roughly 185 million chronic infections, representing individuals at high risk of developing cirrhosis and liver cancer. Given these findings, we investigated the immunity response against HERV‐K and HERV‐W envelope surface (env‐su) glycoprotein antigens in serum and cerebrospinal fluid (... Epstein-Barr virus (EBV) is the main environmental agent associated to neuromyelitis optica spectrum disorder (NMOSD). Methods: Since it's well established that different strains of prions are linked to different conformat... We describe the case of a woman who came to our attention for acute onset and very rapidly worsening left hemiplegia, vision loss and cognitive impairment. Following exclusion of other possible etiologies, a diagnosis of Marburg's var... A novel neuronal tauopathy, mainly confined to hypothalamus and brainstem tegmentum, has recently been reported in patients with autoantibodies to the neuronal cell-adhesion molecule IgLON5. In the present study, we further characterize the conformational p... Background Disrupted autonomic control in spinal cord injury, 57. Background: Anti-IgLON5 disease is a rare neurodegenerative tauopathy that displays heterogeneity in clinical spectrum, disease course, cerebrospinal fluid (CSF) findings, and variable response to immunotherapy. Nowadays polio prior patients (PP) suffer from polio sequelae or have developed post-polio-syndrome (PPS) with increasing paresis, pain and fatigue. Cite . ????? Methods Peripheral and/or central mechanisms may be involved in the genesis of post-traumatic gustatory dysfunction. Centro Interdipartimentale LURM Policlinico G.B. Chronic hepatitis C virus (HCV) infection is commonly associated with neurocognitive dysfunction, altered neuropsychological performance and neuropsychiatric symptoms. Besides, it plays an important role in the error monitoring mechanisms during bimanual coordination. In adults the core clinical feature is usually characterised by acute myelitis and/or optic neuritis. The test... Background: The degree of paresis was compared between... Background: Assessment of laser evoked potentials in normal population, Anti-Ma-associated encephalomyeloradiculopathy in a patient with pleural mesothelioma, Late-onset multiple sclerosis presenting with cognitive dysfunction and severe cortical/infratentorial atrophy, HCV-Related Central and Peripheral Nervous System Demyelinating Disorders, Review of West Nile virus epidemiology in Italy and report of a case of West Nile virus encephalitis, A Test for Creutzfeldt-Jakob Disease Using Nasal Brushings. Methods: Nowadays polio prior patients (PP) suffer from polio sequelae or have developed post-polio-syndrome (PPS) with increasing paresis, pain and fatigue. Neurological complications are thought to be immune-mediated or secondary to invasion of neural tissues by HCV, as postulated in tran... West Nile virus (WNV) is a flavivirus that causes neurological disorders in less than 1 % of infected subjects. codon 129 of the prion protein gene. Nationality. However, it has not been evaluated to date in patients with neuromyelitis optica spectrum disorder (NMOSD). Sorry, you need to be a researcher to join ResearchGate. and Zanusso, Gianluigi (correl.) Demyelinating diseases of the central nervous system associated with autoantibodies against aquaporin-4 and myelin-oligodendrocyte-glycoprotein are mediated by different immunopathological mechanisms compared to multiple sclerosis. J. Mol. salvatore monaco univr it Not present since Note . Objective: He made his professional debut in the Lega Pro for Grosseto on 8 November 2014 in a game against Savona.. On 31 July 2019, he joined Cosenza on loan.. References Salvatore Monaco, Sara Mariotto, Sergio Ferrari, Massimiliano Calabrese, Gianluigi Zanusso, Alberto Gajofatto, Domenico Sansonno, Franco Dammacco ... 37134 Verona, Italy. J. Mol. variability, which is influenced by the conformation of the pathologic prion protein and the methionine/valine polymorphic Peripheral neuropathy (PN), the major neurological complication of chronic HCV infection, is frequently associated with mixed cryoglobulinemia (MC) and small-vessel systemic vasculitis.

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